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Smart Inject Mark 2
Smart Inject Mark 2
A device that automatically performs simultaneous tail vein
injection in up to 8 laboratory animals using a collaborative
robot with equipped withe an AI camera.
AI Camera
Robot Arm
Animal Restraint Device
Injector
Animal Restraint Device
Method of Use
Method of Use
Fixation of anesthetized rat/mouse
(up to 8 animals)
Imaging with Artificial Intelligence camera
(Application of vision machine learning algorithm)
Align with the tail vein location
and move to the robot arm
Needle detection and fine tuning
Tail vein injection
Sequential administration to the animals after the rotation plate operation
1 Robot arm
4 Robot arms
With the option to add up to 4 additional robot arms
Innovative Features
Simultaneous Multi-Animal Administration
Smart Inject Mark 2 can administer drugs to up to 8 laboratory animals simultaneously, drastically increasing experimental efficiency and allowing researchers to collect more data in less time.
Smart Inject Mark 2 can administer drugs to up to 8 laboratory animals simultaneously, drastically increasing experimental efficiency and allowing researchers to collect more data in less time.
Advanced Needle Positioning System
By replacing traditional pressure sensors, Smart Inject Mark 2 integrates advanced technologies such as non-contact flow sensors, ultrasonic sensors, accelerometers, and image processing to detect needle positioning externally. This system eliminates contamination risks during drug loading and significantly improves drug administration accuracy, achieving a success rate of over 90%.
Figure 1. Performance vs. model efficiency on ADE20K. Adapted from "SegFormer: Simple and Efficient Design for Semantic
Segmentation with Transformers," by X. Liu et al., 2021, *arXiv preprint*. Retrieved from https://arxiv.org/abs/2105.15203
Fusion of AI and Robotics
Smart Inject Mark 2 combines AI-driven vein detection with 6-axis robotic arm control, maximizing precision in drug administration. The system uses the Vision Transformer-based SegFormer model to enhance the identification of veins and needle placement, achieving a target accuracy (mIoU) of over 0.9 and real-time processing at 30 FPS, reducing experimental failure rates and improving data reliability.
Animal Restraint Device
Tail Restrainer
Anesthesia-Free Application
Smart Inject Mark 2 enables precise drug delivery without anesthesia, making it suitable for studies where anesthesia is not recommended, such as immune response research, metabolic studies, and behavioral experiments, thus reducing
Experiment
Pre-injection
Start injection
Post-injection
(Success)
(Failure)
(A)
Tail intravenous (I.v) injection of 8% Evans blue by automated administrator.
(A) Injection process images of success injection and failure injection.
White arrows indicate the Evans blue flowing the vein in success injection.
Pre-injection
Post-injection
Pre-injection
Post-injection
(B)
(B) Representative images of SD-
rats that received I.v injection, sho
wing blue coloration of their eyes,
ears, nose, and paws only following success injection.
(Success)
(Failure)
(C)
(C) Pre- and post-injection images of success and failure case.
Product Competitiveness
Administration accuracy achieved more than 90% or higher
Enhancement in the accuracy
of tail vein positioning
Machine learning-based
image processing
Application of algorithm
Improved administration accuracy
Vein identification for AI
3D-scan library of
experiment animal
In-house development of 3D animal
immobilizing apparatus
by establishing an animal library
Diversification of
administration routes
Implementation of multi-angle,
multi-route administration solution
using a 6-axis robotic arm
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