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smart inject
Smart Inject
Smart Inject
A device that automatically performs administration in the
tail veins using a collaborative robot with AI camera.
Animal
Restraint Device
Injector
Edge Computer
Robot Arm
AI Camera
Method of Use
Fixation of anesthetized rat/mouse
Imaging with Artificial Intelligence camera
(Application of vision machine learning algorithm)
Align with the tail vein location
and move to the robot arm
Needle detection and fine tuning
Tail vein administration
Experiment
Green Line : Needle , Red Line : Tail vein
Injection of 50 μl of saline solution
Artificial Intelligence aligns tail vein and needle, and a collaborative robot
controlled by GUI in 0.01mm increments automatically injects drugs.
(A)
(B)
Tail vein recognition using vision machine learning
(A) Tail vein recognition. Rat tail(left), vein recognized as red line(right).
(B) Schematic of U-net image segmentation model.
(Success)
(Failure)
Pre-injection
Start injection
Post-injection
(A)
Tail intravenous (I.v) injection of 8% Evans blue by automated administrator.
(A) Injection process images of success injection and failure injection.
White arrows indicate the Evans blue flowing the vein in success injection.
Pre-injection
Post-injection
Pre-injection
Post-injection
(B)
(B) Representative images of SD-
rats that received I.v injection, sho
wing blue coloration of their eyes,
ears, nose, and paws only followin
g success injection.
(Success)
(Failure)
(C)
(C) Pre- and post-injection images of success and failure case.
Product Competitiveness
Administration accuracy achieved more than 90%
Enhancement in the accuracy
of tail vein positioning
Machine learning-based
image processing
Application of algorithm
Improved administration accuracy
Vein identification for AI
3D-scan library of
experiment animal
In-house development of 3D animal
immobilizing apparatus
by establishing an animal library
Diversification of
administration routes
Implementation of multi-angle,
multi-route administration solution
using a 6-axis robotic arm
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