Smart Inject

Smart Inject

A device that automatically performs administration in the
tail veins using a collaborative robot with AI camera.

Animal
Restraint Device

Injector

Edge Computer

Robot Arm

AI Camera

Method of Use

Fixation of anesthetized rat/mouse

Imaging with Artificial Intelligence camera
(Application of vision machine learning algorithm)

Align with the tail vein location 
and move to the robot arm

Needle detection and fine tuning

Tail vein administration

Experiment

Green Line : Needle  ,  Red Line : Tail vein
Injection of 50 μl of saline solution


Artificial Intelligence aligns
tail vein and needle, and a collaborative robot 
controlled by GUI in 0.01mm increments automatically injects drugs.

(A)

(B)

Tail vein recognition using vision machine learning

(A) Tail vein recognition. Rat tail(left), vein recognized as red line(right).

(B) Schematic of U-net image segmentation model.

(Success)

(Failure)

Pre-injection

Start injection

Post-injection

(A)

Tail intravenous (I.v) injection of 8% Evans blue by automated administrator. 

(A) Injection process images of success injection and failure injection. 
White arrows indicate the Evans blue flowing the vein in success injection.

Pre-injection

Post-injection

Pre-injection

Post-injection

(B)

(B) Representative images of SD-
rats that received I.v injection, sho

wing blue coloration of their eyes, 
ears, nose, and paws only followin
g success injection.

(Success)

(Failure)

(C)

(C) Pre- and post-injection images of success and failure case.

Product Competitiveness

Administration accuracy achieved more than  90%

Enhancement in the accuracy 
of tail vein positioning

 Machine learning-based 
image processing 
Application of algorithm
 

Improved administration accuracy

 Vein identification for AI  

3D-scan library of
experiment animal

 In-house development of 3D animal
immobilizing apparatus 
by establishing an animal library
 

Diversification of
administration routes

 Implementation of multi-angle,
multi-route administration solution
using a 6-axis robotic arm