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smart inject

Smart Inject

Smart Inject

A device that automatically performs injection in the
tail veins using a collaborative robot with AI camera.


Restraint Device

Robot Arm

AI Camera

Method of Use

Fixation of anesthetized rat/mouse

Imaging with Artificial Intelligence camera
(Application of vision machine learning algorithm)

Align with the tail vein location 
and move to the robot arm

Needle detection and fine tuning

Tail vein injection


Green Line : Needle  ,  Red Line : Tail vein
Injection of 50 μl of saline solution

Artificial Intelligence aligns
tail vein and needle, and a collaborative robot 
controlled by GUI in 0.01mm increments automatically injects drugs.



Tail vein recognition using vision machine learning

(A) Tail vein recognition. Rat tail(left), vein recognized as red line(right).

(B) Schematic of DeepLab V3+ image segmentation model. 


Start injection



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Tail intravenous (I.v) injection of 8% Evans blue by automated administrator. 

(A) Injection process images of success injection and failure injection. 
White arrows indicate the Evans blue flowing the vein in success injection.






(B) Representative images of SD-
rats that received I.v injection, sho

wing blue coloration of their eyes, 
ears, nose, and paws only following success injection.




(C) Pre- and post-injection images of success and failure case.

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Figure 1. Accurate entry into the tail vein can be confirmed through chandes in the pressure value inside the needle.

While drug injection is in progess by AIIS, the pressure sensor value inside the needle changes in a certain pattern, and the success of insertion into the tail vein can be judged through the change in pressure value. If needle insertion into the tail vein was successful, a pressure value of 7mmHg or more was observed, and a pattern was observed where the pressure rose during injection and then fell again when drug injection was completed.

카달로그(영문)제작용_데이터시트 수정-13.jpg

Figure 2. Tail vein recognition using vision machine learning.

(A) Schematic of Deeplabv3+ image segmentation model. (B) Tail vein recognition within the GUI. Vein recognized as green line, needle recognized as red line. Accurate injection positioning with automatic adjustment of tail vein and needle position by AI. 

Product Competitiveness

Administration accuracy achieved more than  90% or higher

Enhancement in the accuracy 
of tail vein positioning

Machine learning-based 
image processing 
Application of algorithm

Improved administration accuracy

Vein identification for AI 

3D-scan library of
experiment animal

In-house development of 3D animal
immobilizing apparatus 
by establishing an animal library

Diversification of
administration routes

Implementation of multi-angle,
multi-route administration solution
using a 6-axis robotic arm

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